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Propylene Oxide

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    Specialty Chemicals

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Product Profile

Propylene Oxide (1,2-Epoxypropane)

   CAS No.: 75-56-9
   IUPAC / Synonyms: Propylene Oxide, 1,2-Epoxypropane, Methyloxirane


Physicochemical Properties (Typical)

  • Appearance: Colorless, clear liquid
  • Odor: Ether-like, slightly sweet
  • Molecular Formula: C₃H₆O
  • Molecular Weight: 58.08 g/mol
  • Melting / Freezing Point: ~ –112.0 °C
  • Boiling Point: ~34.0–35.0 °C
  • Density (20–25 °C): ~0.83 g/cm³
  • Vapor Pressure (20 °C): ~445 mmHg
  • Flash Point: ~–37 °C (closed cup)
  • Autoignition Temperature: ~430 °C
  • Explosive / Flammable Limits (v/v in air): ~1.9% – 36%
  • Solubility in Water (20 °C): ~40 g / 100 mL (partially miscible)
  • Refractive Index (n²⁰ᴰ): ~1.366
  • Log P (octanol/water): ~0.03

Purity & Quality Standards

  • Purity (e.g. by GC): ≥99.0%
  • Water / Moisture Content: ≤0.5%
  • Volatile Impurities: Controlled within strict limits
  • Acid / Base Impurities: Minimal
  • Heavy Metals: ≤0.001% (typical)
  • Analytical Methods: Gas chromatography, spectroscopy, titration
  • Documentation: COA and SDS provided

Applications / Uses

  • Intermediate in production of polyether polyols (for polyurethanes)
  • Manufacture of propylene glycol, glycol ethers, and propylene carbonate
  • Solvent or reagent in organic syntheses
  • Fumigant / sterilization agent in some controlled applications
  • Additive for coatings, adhesives, lubricants, surfactants

Safety & Handling

  • Hazard Class: Extremely flammable liquid and vapor
  • Health Hazards: Irritating to eyes, skin, respiratory tract; may depress CNS at high exposure; probable human carcinogen
  • Exposure Limits: TLV / OSHA ~20 ppm; IDLH ~2,000 ppm
  • Precautions: Use in well-ventilated area; wear gloves, goggles, respiratory protection
  • Fire & Explosion: Vapor may form explosive mixtures; avoid ignition sources and static
  • Reactivity / Incompatibilities: Strong oxidizers, acids, bases, metal catalysts, peroxides
  • Hazardous Polymerization: May polymerize under elevated temperature, catalysts, or with contaminants
  • First Aid: Inhalation - fresh air; Skin - rinse with water; Eyes - flush with water; Ingestion - seek medical attention

Packaging & Storage

  • Packaging: Sealed, compatible containers (metal drums, lined vessels)
  • Storage Conditions: Cool, dry, well-ventilated area away from heat, flame, sunlight
  • Container Closure: Keep tightly sealed
  • Storage Temperature: Often under inert gas (e.g. nitrogen)
  • Shelf Life: 12–24 months under proper storage