Dimethyl Sulfoxide
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Category:
Specialty Chemicals
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Product Profile
1. Chemical Structure and Properties
Molecular Formula: C₂H₆OS
Structural Formula: (CH₃)₂SO — DMSO is a polar aprotic solvent with a sulfoxide functional group.
Physical Properties:
Appearance: Colorless, hygroscopic liquid
Boiling Point: 189°C
Density: 1.1 g/cm³ at 20°C
Solubility: Miscible with water, alcohols, and most organic solvents
Chemical Properties:
Highly polar aprotic solvent
Can stabilize anions and participate in nucleophilic substitution reactions
Chemically stable under normal conditions but may react with strong oxidizers
2. Industrial Applications
Solvent in Chemical Synthesis: Widely used in pharmaceutical and polymer synthesis due to its excellent solvating properties
Cryopreservation: Used to preserve cells, tissues, and organs in biomedical research
Electronics Industry: Functions as a cleaning solvent and reagent in manufacturing processes
Analytical Chemistry: Utilized as a solvent in NMR spectroscopy and other analytical techniques
3. Safety and Toxicology
Health Hazards: May cause skin irritation and enhance absorption of other chemicals through skin
Inhalation: Vapors may irritate respiratory tract
Protective Measures: Use gloves, goggles, and adequate ventilation; avoid direct skin contact
4. Environmental and Regulatory Considerations
Environmental Impact: Biodegradable under aerobic conditions; avoid discharge into waterways in large quantities
Regulatory Compliance: Listed on EU REACH and US TSCA inventories; transport as non-hazardous liquid under standard conditions
5. Case Studies and Application Insights
Pharmaceutical Synthesis: DMSO serves as a solvent for polar reactants, improving reaction yields and selectivity
Cryobiology: Used successfully to preserve stem cells and other biological samples without significant loss of viability