TETRAMETHYL ETHYLENEDIAMINE
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Category:
Specialty Chemicals
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Product Profile
Product Overview
Tetramethylethylenediamine (TMEDA), also known as TEMED, is a tertiary diamine widely used as a ligand, catalyst, polymerization accelerator, and biochemical reagent. It is supplied as a clear, colorless liquid that may gradually develop a yellow coloration during prolonged storage.
TMEDA is particularly valued for its strong metal-chelating ability and its role in polymerization systems, organometallic chemistry, pharmaceutical synthesis, and molecular biology applications. It forms stable complexes with many metal ions and is one of the most commonly used diamine ligands in laboratory and industrial chemistry.
Applications
Pharmaceuticals
TMEDA is widely used in pharmaceutical synthesis, API production, and fine chemical manufacturing.
| Application Area | Typical Uses |
|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of pharmaceutical intermediates |
| API Synthesis | Applied in active pharmaceutical ingredient production |
| Organometallic Reactions | Used in metal-mediated pharmaceutical synthesis |
| Metal-Complex Catalysis | Functions as a ligand in catalytic systems |
| Fine Chemical Manufacturing | Used in specialty and fine chemical production |
Catalyst & Polymerization
| Application Area | Typical Uses |
|---|---|
| Polymerization Accelerator | Promotes polymerization reactions |
| Acrylamide Polymerization | Used as an acrylamide polymerization catalyst |
| Polyacrylamide Gel Production | Essential component for gel preparation |
| Radical Polymerization Systems | Used in radical polymerization formulations |
| Catalyst Formulations | Applied in specialized catalyst systems |
Biochemistry & Molecular Biology
| Application Area | Typical Uses |
|---|---|
| PAGE Applications | Polyacrylamide Gel Electrophoresis |
| Protein Separation | Used in electrophoresis gel systems |
| DNA & RNA Analysis | Supports nucleic acid analysis workflows |
| Electrophoresis Gel Preparation | Used in gel preparation and reagent systems |
| Laboratory Reagent Formulations | Used in biochemical and molecular biology reagents |
Chemical Synthesis
| Application Area | Typical Uses |
|---|---|
| Metal Ion Ligand | Forms stable complexes with metal ions |
| Organolithium Chemistry | Used in organolithium reaction systems |
| Grignard Reactions | Applied in organometallic synthesis |
| Organometallic Catalysts | Used as a ligand in catalyst preparation |
| Specialty Chemical Production | Used in high-value specialty chemical manufacturing |
Physical & Chemical Properties
| Property | Value |
|---|---|
| Chemical Name | Tetramethylethylenediamine |
| Synonyms | TMEDA, TEMED |
| CAS Number | 110-18-9 |
| Molecular Formula | C₆H₁₆N₂ |
| Molecular Weight | 116.21 |
| Appearance | Clear Colorless Liquid |
| Odor | Characteristic Amine Odor |
Specifications
| Item | Specification |
|---|---|
| Purity, GC | ≥ 99.00 wt.% |
| Water Content, KF | ≤ 0.50 wt.% |
Packaging & Transportation
Standard Packaging
| Packaging Type | Net Weight / Description |
|---|---|
| Steel Drum | 180 kg |
| Steel Drum | 190 kg |
| Steel Drum | 200 kg |
| IBC Tank | 1000 kg |
| ISO Tank Container | Bulk Packaging |
Transportation
TMEDA is classified as dangerous goods and is suitable for transportation by sea, road, and rail. It should be handled, loaded, transported, and stored according to applicable international hazardous chemical regulations.
Regulatory Information
| Item | Value |
|---|---|
| CAS Number | 110-18-9 |
| IMDG Class | Class 3 |
| HS Code | 2921.29.90 |
Storage & Handling
Store TMEDA in tightly sealed containers in a cool, dry, and well-ventilated area. Keep away from heat, sparks, flames, and ignition sources.
Avoid contact with copper and copper-containing alloys. Protect the product from moisture and direct sunlight.
The product may gradually develop a yellow coloration during prolonged storage without significantly affecting its performance.
Ensure adequate ventilation during storage, transfer, sampling, and handling operations.
Health & Safety
TMEDA may cause irritation to the skin, eyes, and respiratory system. Avoid direct contact with the product and prevent inhalation of vapors.
In case of skin or eye contact, flush immediately with plenty of water for at least 15 minutes. If inhaled, move the affected person to fresh air and seek medical attention if necessary.
In case of ingestion, obtain immediate medical attention.
Appropriate personal protective equipment should always be used during handling and transfer operations.
Key Advantages
| Advantage | Description |
|---|---|
| High Purity | Minimum 99.0% assay |
| Excellent Ligand | Suitable for metal-ion complex formation |
| Organometallic Use | Widely used in organometallic chemistry |
| Polymerization Performance | Essential catalyst component for polyacrylamide gel preparation |
| Broad Application Range | Suitable for pharmaceutical, biochemical, and laboratory applications |
| Stable Quality | Reliable industrial-grade supply |
| Flexible Packaging | Available in drum, IBC, and ISO tank packaging |
| Global Logistics Support | Supported by professional hazardous chemical logistics services |
Product Description
Tetramethylethylenediamine (TMEDA) is a high-purity tertiary diamine supplied as a clear, colorless liquid with excellent ligand and catalytic properties. It is extensively used in pharmaceutical synthesis, organometallic chemistry, polymerization systems, and biochemical applications such as polyacrylamide gel electrophoresis.
With strong metal-chelating capability, high purity, and reliable quality, TMEDA is an essential reagent for laboratories, research institutions, and industrial chemical manufacturers worldwide.