MONOISOPROPYLAMINE (MIPA)
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Category:
Aliphatic Amines
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China Amines Co
Product Profile
1. Chemical Structure and Properties
- Chemical Name: Monoisopropylamine (MIPA)
- Synonyms: Isopropylamine, 2-Aminopropane
- CAS No.: 75-31-0
- Molecular Formula: C₃H₉N
- Molecular Weight: 59.11 g/mol
- Appearance: Colorless to pale yellow liquid
Odor: Strong, ammonia-like odor
- Boiling Point: 32–33 °C
- Melting Point: –89 °C
- Density (20 °C): 0.69 g/cm³
- Solubility: Miscible with water, alcohols, and ether
Reactivity: Highly flammable; reacts with acids to form salts; may form explosive mixtures with air
2. Industrial Applications
- Agrochemicals: Intermediate in herbicides, pesticides, and plant growth regulators
- Pharmaceuticals: Building block for active pharmaceutical ingredients (APIs)
- Chemical Intermediates: Precursor for isopropylamine derivatives, surfactants, and quaternary ammonium compounds
- Rubber & Polymers: Used as vulcanization accelerators and polymerization catalysts
Water Treatment: Component in corrosion inhibitors and other chemical formulations
3. Safety and Toxicology
Hazards:
- Skin: Causes severe irritation or burns
- Eyes: Causes serious eye damage
- Inhalation: Vapors irritate respiratory tract; high concentrations may cause pulmonary edema
- Ingestion: Harmful, may cause burns to mouth and gastrointestinal tract
Toxicity:
- Oral LD₅₀ (rat): ~206 mg/kg
- Dermal LD₅₀ (rabbit): ~820 mg/kg
- Inhalation LC₅₀ (rat, 4h): ~4,500 ppm
Flammability: Highly flammable liquid and vapor (Flash point: –22 °C, Closed cup)
PPE: Chemical-resistant gloves, goggles, face shield, protective clothing, and respiratory protection; ensure good ventilation
4. Storage and Handling
- Storage: Store in tightly sealed containers, in a cool, dry, well-ventilated area; keep away from heat, sparks, and open flames
- Packaging: Steel drums, IBC tanks, or bulk tankers
- Handling: Avoid inhalation of vapors; use explosion-proof equipment; ensure grounding during transfer
Shelf Life: Stable under recommended storage conditions, sensitive to moisture and CO₂
5. Environmental and Regulatory Compliance
Environmental Impact:
- Toxic to aquatic organisms; potential for environmental damage if released
- Volatile and flammable, handle with care
Regulations:
- EU CLP: Flam. Liq. 2 (H225), Acute Tox. 3 (H301, H311, H331), Skin Corr. 1B (H314)
- OSHA (USA): Classified as hazardous chemical
- China GB 13690-2009: Flammable and corrosive substance
Transport:
- UN No.: 1284
- Hazard Class: 3 (Flammable liquid) with corrosive risk
- Packing Group: II