Ethylene glycol monoethyl ether acetate (Cellosolve® acetate)

   CAS No.: 111-15-9
   Synonyms / IUPAC Name: Ethylene glycol monoethyl ether acetate; Cellosolve® acetate; 2-ethoxyethyl acetate
   Molecular Formula: C₆H₁₂O₃
   Molecular Weight: ≈ 132.16 g/mol

Physicochemical Properties (Typical)

• Appearance: Clear, colourless liquid.
• Odour: Mild ester-like / ether-like.
• Melting / Freezing Point: ~ −61 °C.
• Boiling Point: ~ 156 °C (at 760 mmHg).
• Density (20–25 °C): ~ 0.975 g/cm³.
• Vapour Pressure: ~2 mmHg (≈0.27 kPa) at 20 °C.
• Solubility in Water: ~230 g/L (≈6 parts in water at 20 °C).
• Flash Point: ~ 54–57 °C (closed cup).
• Explosive Limits: Lower ≈ 1.7% vol; Upper ≈ 6.7–10% vol.

Purity & Quality Standards

• Typical Purity: ≥ 98% for high-grade solvent applications.
• Appearance: Clear, free from visible particulates or haze.
• Analytical Methods: Gas chromatography for assay; moisture and non-volatile residue monitored.
• Stability: Stable under recommended storage conditions; sensitive to ignition sources and strong oxidisers.

Applications / Uses

• Industrial solvent for coatings, inks, lacquers, resins, cleaning and degreasing fluids.
• Intermediate in chemical reactions where both ether and ester functionalities are utilized.
• Formulation solvent where moderate polarity and evaporation characteristics are required.

Safety & Handling

• Flammable liquid and vapour — vapour may form explosive mixtures with air.
• Inhalation: May cause respiratory irritation and dizziness.
• Skin Contact: May cause irritation; skin absorption possible.
• Eye Contact: Causes serious eye irritation.
• Reproductive Toxicity: May damage fertility or the unborn child (animal data).
• Precautions:
• Use in well-ventilated areas or local exhaust ventilation.
• Keep away from heat, sparks, open flames and hot surfaces; ground and bond containers during transfer.
• Wear protective gloves, eye/face protection and suitable protective clothing.
• Reactivity / Incompatibilities: Avoid strong oxidising agents, strong acids, strong bases and nitrates.
• First Aid:
• Inhalation: Move to fresh air; keep at rest; seek medical attention if symptoms persist.
• Skin Contact: Remove contaminated clothing; wash thoroughly with soap and water.
• Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present; seek medical attention.
• Ingestion: Rinse mouth; do not induce vomiting; seek medical attention immediately.

Packaging & Storage

• Packaging: Supplied in sealed solvent-compatible containers suitable for flammable liquids.
• Storage Conditions: Store in a cool (< 30 °C), dry, well-ventilated area away from ignition sources, direct sunlight and incompatible materials. Keep containers tightly closed when not in use.
• Shelf Life: Typically 12–24 months under recommended storage; inspect for colour or odour changes before use.
• Transport: Classified as Flammable Liquid (UN 1172); handle per applicable transport regulations.