Butyl 2-hydroxyacetate (n-butyl glycolate)

   CAS No.: 7397-62-8
   Synonyms / IUPAC Name: Butyl 2-hydroxyacetate; n-butyl glycolate
   Molecular Formula: C₆H₁₂O₃
   Molecular Weight: ≈ 132.16 g/mol

Physicochemical Properties (Typical)

• Appearance: Clear to very faint yellow liquid
• Odor: Mild ester-like/faintly fruity (typical of glycolate esters)
• Boiling Point: Approx. 187–190 °C
• Density (20 °C): Approx. 1.019 g/mL
• Refractive Index (n²⁰ᴰ): Approx. 1.427
• Solubility: Limited in water (≈ 46 g/L at 20 °C)
• Flash Point: Approx. 74–75 °C (closed cup)

Purity & Quality Standards

• Purity: High-grade material typically ≥ 98% (GC) for advanced applications
• Appearance: Clear to very light yellow liquid, free of particulates
• Analytical Methods: Gas chromatography (GC) for assay and purity; spectral confirmation for structure
• Stability: Contains stabilisers/inhibitors to minimise polymerisation and decomposition during storage

Applications / Uses

• Function as a solvent, coalescent or additive in coatings, varnishes, and alkyd resins due to its ester structure and moderate polarity
• Intermediate in speciality chemical synthesis, where hydroxyl and ester functionalities are required
• May serve as a wetting agent or plasticiser component in certain formulations due to its ester/hydroxyl dual-function

Safety & Handling

• Hazard Classification: Liquid with combustible properties; may cause serious eye damage and suspected fertility or reproductive toxicity
• Health Hazards:
• Eye Contact: Causes serious eye damage
• Skin/Inhalation: May cause irritation; vapours or mists may affect respiratory tract
• Precautions:
• Use with adequate ventilation; avoid vapour accumulation
• Keep away from heat, sparks, open flames and hot surfaces; ground and bond containers during transfer
• Wear chemical-resistant gloves, eye/face protection, and suitable protective clothing
• Reactivity / Incompatibilities: Avoid strong oxidising agents, bases, and prolonged heat exposure. Ensure proper handling to prevent decomposition
• First Aid Measures:
• Eye Contact: Rinse cautiously with water for several minutes; seek medical attention if irritation persists
• Skin Contact: Remove contaminated clothing; wash thoroughly with soap and water
• Inhalation: Move to fresh air; keep at rest; seek medical attention if symptoms continue
• Ingestion: Rinse mouth; do not induce vomiting; obtain medical advice

Packaging & Storage

• Packaging: Supplied in sealed steel or lined containers compatible with ester solvents and combustible liquids
• Storage Conditions: Store in a cool (<30 °C), dry, well-ventilated area; keep containers tightly closed; protect from sunlight and ignition sources
• Shelf Life: Typically stable for 12–24 months under proper storage conditions; inspect for colour change or container integrity prior to use
• Transport: Classify as combustible/flammable liquid; follow applicable regulations for shipping