ACETONITRILE
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Category:
Specialty Chemicals
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Product Profile
Product Overview
Acetonitrile (MeCN), also known as Methyl Cyanide, is the simplest aliphatic nitrile and one of the most important high-purity industrial solvents used worldwide. Due to its excellent solvency, low viscosity, high polarity, and favorable chromatographic properties, Acetonitrile is extensively utilized in pharmaceutical manufacturing, analytical laboratories, biotechnology, petrochemicals, and chemical synthesis.
Acetonitrile is particularly valued as the preferred solvent for HPLC (High-Performance Liquid Chromatography), peptide synthesis, and biologics purification processes.
Applications
Pharmaceutical Industry
| Application Area | Typical Uses |
|---|---|
| API Manufacturing | Solvent for active pharmaceutical ingredient production |
| Pharmaceutical Intermediates | Process solvent for intermediate synthesis |
| Drug Purification | Purification and separation processes |
| Peptide Synthesis | Reaction and purification solvent |
| Pharmaceutical Processing | General process solvent |
Analytical & Laboratory Use
| Application Area | Typical Uses |
|---|---|
| HPLC | High-purity chromatographic solvent |
| LC-MS | Mobile phase solvent for analytical applications |
| Chromatographic Analysis | Separation and detection processes |
| Analytical Reagent | Laboratory-grade reagent use |
| Laboratory Synthesis | Solvent for research and synthesis work |
Biotechnology & Life Sciences
| Application Area | Typical Uses |
|---|---|
| Biologics Purification | Solvent for purification processes |
| Protein Analysis | Analytical and sample preparation applications |
| Diagnostic Reagent Manufacturing | Solvent or processing aid |
| Research Applications | Biotechnology and life science research |
Chemical Industry
| Application Area | Typical Uses |
|---|---|
| Petrochemical Processing | Extraction and processing solvent |
| Extraction Solvent | Separation and purification applications |
| Organic Synthesis | Reaction solvent and synthesis medium |
| Fine Chemical Manufacturing | Solvent for specialty chemical production |
| Catalyst & Reaction Medium | Used in various chemical reactions |
Physical & Chemical Properties
| Property | Value |
|---|---|
| Chemical Name | Acetonitrile |
| Synonyms | MeCN, Methyl Cyanide, Cyanomethane |
| CAS Number | 75-05-8 |
| Molecular Formula | C₂H₃N |
| Structural Formula | CH₃CN |
| Molecular Weight | 41.05 |
| Appearance | Clear, Colorless Liquid |
| Specific Gravity, 20°C | 0.775 – 0.785 |
| Refractive Index, 20°C | 1.452 – 1.454 |
| Boiling Point | 81.6°C |
| Freezing Point | Below -45°C |
| Water Solubility | Soluble |
| Flash Point, Closed Cup | 2°C |
Specifications
| Item | Specification |
|---|---|
| Purity, GC | ≥ 99.9 wt.% |
| Appearance | Clear, Colorless Liquid |
| Color, APHA | ≤ 10 |
| Specific Gravity @ 20°C | 0.780 – 0.785 |
| Water Content, KF | ≤ 0.05 wt.% |
| Acetone | ≤ 0.005 wt.% |
| Free Ammonia | ≤ 0.0006 wt.% |
| Propionitrile | ≤ 0.03 wt.% |
| Acrylonitrile | Not Detected |
| Acidity, as Acetic Acid | ≤ 0.05 wt.% |
Packaging & Transportation
Standard Packaging
| Packaging Type | Net Weight / Description |
|---|---|
| Steel Drum | 160 kg |
| Steel Drum | 190 kg |
| Steel Drum | 200 kg |
| IBC Tank | 1000 kg |
| ISO Tank Container | Bulk Packaging |
| Bulk Tank Shipment | Available for large-volume orders |
Transportation
Acetonitrile is classified as dangerous goods and is suitable for transportation by sea, road, rail, and air. It should be handled, stored, loaded, and transported according to applicable international hazardous chemical regulations.
Regulatory Information
| Item | Value |
|---|---|
| CAS Number | 75-05-8 |
| IMDG Class | Class 3 |
| HS Code | 2926.90.00 |
Storage & Handling
Store Acetonitrile in tightly sealed containers in a cool, dry, and well-ventilated area. Keep away from heat, sparks, flames, and all ignition sources.
Protect the product from direct sunlight and excessive temperatures. Use explosion-proof equipment and proper grounding systems where required.
Avoid contact with strong oxidizing agents. Ensure adequate ventilation during storage, transfer, sampling, and handling operations.
Health & Safety
Acetonitrile is a highly flammable liquid and vapor. Avoid inhalation of vapors and direct skin or eye contact.
Use appropriate personal protective equipment, including chemical-resistant gloves, safety goggles, protective clothing, and respiratory protection where necessary.
In case of skin or eye contact, rinse immediately with plenty of water. If inhaled, move the affected person to fresh air and seek medical attention if symptoms persist.
Follow all applicable industrial safety regulations during handling, storage, transfer, and transportation.
Key Advantages
| Advantage | Description |
|---|---|
| High Purity | Minimum 99.9% assay |
| Analytical Performance | Preferred solvent for HPLC and LC-MS applications |
| Excellent Solvency | Suitable for pharmaceutical, laboratory, and chemical use |
| Chemical Stability | Stable performance in various industrial processes |
| Low Impurity Level | Suitable for pharmaceutical and analytical applications |
| Biotechnology Use | Widely used in biologics purification and peptide synthesis |
| Flexible Packaging | Available in drums, IBC tanks, ISO tanks, and bulk shipments |
| Global Supply | Reliable quality and worldwide supply capability |
| Logistics Support | Supported by professional hazardous chemical logistics |
Product Description
Acetonitrile (MeCN) is a high-purity polar aprotic solvent widely used in pharmaceutical production, analytical chemistry, biotechnology, and petrochemical processing. With a minimum purity of 99.9%, low water content, and exceptional chromatographic performance, Acetonitrile is the solvent of choice for HPLC, LC-MS, peptide synthesis, and biologics purification.
Its excellent solvency, consistent quality, and broad industrial applicability make Acetonitrile an essential material for laboratories and manufacturing facilities worldwide.